Im a 37 year old female. i had my first IBS flare up, or so they called it, like 2 years ago. That time symptoms were constant pain in the left lower quadrant and constipation. It lasted for two months. The second flare up was just 3 months after my first pregnancy. Symptoms this time changed. I started experiencing constant diarrhea and pain in the left upper quadrant. i had several tests like blood tests, cancer markers, upper and lower abdominal ultrasound, stool samples for parasites, all came up clear. My GP and gastroenterlogist insist that i have IBS.